Diagnosis

How is PAO diagnosed?
  • Diagnosis is usually confirmed by the identification of vertebral fractures on a spinal x-ray or MRI scan.

    • Important! Fractures do not always show up on an x-ray alone.

  • Women suspected of having PAO will usually be referred for a bone mineral density (DEXA) scan. This may show reduced bone density, particularly in the lumbar spine. Research studies have consistently shown a greater reduction in lumbar spine bone density compared with hip bone density in PAO.

    • Important! Sometimes a bone density measurement of the lumbar spine may not be informative, as it is difficult to accurately measure bone density at this site in people with multiple vertebral fractures.

a large white MRI machine
a large white MRI machine
What are the signs & symptoms of PAO fractures?
grayscale photo of woman in white button up shirt showing spine prominently
grayscale photo of woman in white button up shirt showing spine prominently
  • For most women, the first sign of PAO is back pain, as spinal fractures are the most common type of PAO fracture.

    • Important! The type of pain experienced can vary greatly between individuals.

  • Typically, women with PAO experience severe pain that makes it difficult or impossible for them to continue with their usual activities.

  • Pain may start suddenly, sometimes after movements such as lifting or reaching.

  • Many women with PAO experience more than one spinal fracture before the condition is diagnosed. This can result in a change in the shape of the spine (forward bend or kyphosis) and/or loss of height (sometimes several inches).

  • Significant back pain starting during late pregnancy or shortly after delivery and/or loss of height should be considered red flags for possible PAO and would be reasons to seek prompt medical attention.